Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. Ewe eje can also be used to manage abnormalities associated with anaemia and for the treatment and management of diabetics. Other English names for this plant include: flamingo flower, Jacobinia, Brazilian plume flower and Brazilian plume. The gradual decrease in the weight of organs following short-term exposure of J. carnea leaf ethanol extract may be attributed to adaptive response of the organs arising from daily dosage of the extract or its metabolites within their body. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. 2003;84:99104. Star Apple: Amazing Health Benefits of eating its fruits. Maturitas 2010;66(3):315-322. Acta Scientiarum Polonorum, Technologia Alimentaria. View abstract. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. A., Bezerra, G. A., Matos, F. J., and Viana, G. S. Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. https://doi.org/10.13040/IJPSR.0975-8232. Authors TSO, KOK and ESA manage experimental protocols and performed the experiments under the supervision of FOA. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. This is attributed to the anti-hyperlipidaemic properties of the plant. W Afr J Biol Sci. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. Pot the specimen and bring it indoors to add a bright touch of color to your interiors. How to make Ewe eje Extracthow to prepare justicia carnea. CAS degree in Biochemistry fromUniversity of Ado-Ekiti, Ekiti State, Nigeria and University of Ibadan, Nigeriarespectively. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. How long does it take for Aju mbaise to work. The mixture was incubated at 28C for 30min and the absorbance read at 550nm against the reagent blank. The lush foliage and distinctive flowers make Brazilian Plume a natural for a . What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. It is believed by local consumers in Ghana to possess anti-anaemic effects that boost blood levels in pregnant women, anaemic patients and also . Backfill the soil gently, filling the empty space around the root ball and then press it down with your hands. Antianaemic potentials of some plant extracts on phenyl hydrazineinduced anemia in rabbits. 2005;102(2):197201. The findings back up local assertions that they can be. Article Inter J Pharm Sci Res. The Justicia carnea leaves are rich in B-vitamins. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. The absorbance was taken at interval of 1min for 3min at 480nm. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. However, further research needs to done to determine the mode of action of the plant, and it's effects on humans. Nunes TRS, Cordeiro MF, Beserra FG, et al. The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. This study has confirmed the safety of ethanol extract of J. carnea leaf and validates its conventional use as blood booster. Water your plants deeply during growth periods, allowing the soil to dry . Authors KOK and ESA performed the statistical analysis and managed the analyses of study. I also conduct research on molecular basis of human diseases, linking the pharmacological properties of certain natural products and their mechanisms of actions to the treatment of such diseases. The antidiabetic effect of justicia is through the inhibition of-amylase and -glucosidase, the carbohydrate metabolizing enzymes, and also through its hypolipidemic potential. https://doi.org/10.1016/j.jada.2008.06.430. Treatments of experimental animals were in accordance with the Principle of Laboratory Animal Care manual guide of National Institute of Health [14] as approved by the Institution Research Ethics committee. Studies have also confirmed this claim. Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. Cassani, J., Dorantes-Barrn, A. M., Novales, L. M., Real, G. A., & Estrada-Reyes, R. (2014). Relative to control, lymphocyte and granulocyte exhibited no significant difference in all doses while MID was elevated in treated groups with significant increase in rats administered with 500 and 800mg/kg body weight. The kidney of rats treated with doses of J. carnea ethanol extract revealed dose dependent degree of renal injury (Fig. Bottom Line. Phytother Res 2011;25(3):444-450. Olaniyan JM, Hadiza LM, Hussaini AM, Musa BB, Abubakar SA. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). 2016;5(1):6270 https://doi.org/10.1016/j.joad.2015.08.006. It is obvious that Justicia carnea has potential antianemic, antioxidant, antidiabetic, hepatoprotective, and immune-boosting properties. J Am Diet Assoc. This also helps prevent self-seeding, which normally takes up a lot of the plants energy at the expense of flowering. The Pros and Cons of Creatine You Should Know. Also observed is a distortion in the walls of the blood vessels (red arrow), pyknotic hepatocytes and signs of inflammation (red arrow), Photomicrographs of kidney sections stained with Haematoxylin and Eosin (Mag. Privacy 32 years old (Greco et al., 1974), long-term treatment side effects are becoming more critical. When it comes to fertilizing, an NPK balance of 5-10-5 will work well, encouraging blooming and strong growth. Biochemistry Unit, Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria, Emmanuel Sina Akintimehin,Kayode Olayele Karigidi,Tope Samuel Omogunwa&Foluso Olutope Adetuyi, You can also search for this author in Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. Hence, Justicia carnea can be used to strengthen the immune system. However, watch out for nematodes and spider mites. 2. Powdered sample (1000g) was soaked in absolute ethanol (3000mL) with constant stirring. They should be watered regularly (once per week), but not overwatered. National Research Council. In the winter, temperatures between 60 64 degrees Fahrenheit (15 18 C) are ideal. The package will tell you exactly how, when, and how much feed to use. The results of this study suggests that ethanol extract of J. carnea leaf is relatively safe, could be beneficial in alleviating hematology related abnormalities without causing adverse effects on endogenous antioxidant system. Ewe eje is good for the liver. Saunders; 1995. p. 26873. Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. Briefly, 1.0ml of the sample was mixed with 2ml of TCA-TBA-HCl reagent (0.37% thiobarbituric acid, 15% trichloroacetic acid and 0.24N HCl in 1:1:1) and boiled at 100C in a water bath for 15min. 2007;112(1):13844. Afr J Tradit Complement Altern Med. (2017). He has B.Sc.,and M.Sc. 2005 - 2023 WebMD LLC, an Internet Brands company. The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. Generic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. One of the health benefits of justicia carnea is in boosting immune system. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. While vitamin A maintains good vision, vitamin B are good for cellular functions such as metabolisms and energy production, and improve brain functioning. Also, remove old flowers to keep the plant healthy. Dyslipidemia is one of the risk factors of cardiovascular diseases. Safety assessment of oral administration of ethanol extract of Justicia carnea leaf in healthy wistar rats: hematology, antioxidative and histology studies. Philadelphia: WB. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. Google Scholar. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. We use cookies on this website, you can read about them here. These minerals help in boosting blood production, which is why the plant is called ogwu obara (blood medicine) among the Igbo people of Southern Nigeria. 2019;30(4):64554. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. Fertility leaves: Benefits and side effects, Guava Leaf Tea: Health Benefits of Guava Leaves, Coriander seeds: 18 benefits Coriandrum sativum fruits and seeds, Rapini: Nutritional facts, benefits, side effects and care. Biomed Res. Pinch out tips to promote compact plants. This is not a big concern as it wont kill the plant and you will find a solution at your local gardening center. The efficiency of some preexisting anti-obesity drugs was limited by several adverse effects associated with them including gastrointestinal disorder, high risk of cancer, and long-term use detrimental effects on some organs such as liver, kidney and pancreas [ 4, 8 ]. Watering depends on humidity and temperature. 200, 500 and 1000 mg/kg bw of Justicia carnea showed a significant (p<0.05) decrease in the activities of ALT, AST and ALP, and bilirubin level while total protein and albumin levels increased significantly (p<0.05) when compared with the rats treated with CCl alone. The leaves are also rich source of vitamin A, vitamin C, and vitamin E. Another plant with this composition is pumpkin fruit. This requires more attention to properly document the various health benefits of justicia carnea. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants). No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. The significant decrease in kidney GSH at 1200mg/kg could be due to ample dietary bioactive constituents in the extract that requires frequent conjugation of GSH in the cell or oxidation to oxidized glutathione (GSSG). To create additional collections, you must be a paid member of our site. 1. Niger J Physiol Sci. View abstract. 10.9734/ijbcrr/2020/v29i630194. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Part of Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. 2011;5(9):48992 https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867. 2013;1:38898. PubMed Fitoterapia. 2008;108(9):14807. One of the oldest known plant is the fig tree. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). The renal tubules and interstitial spaces appears distorted with presence of red inflammatory cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane. The cuttings are taken from the parent plant in the spring after the plant has bloomed. BMC Complem Altern Med. The minerals present in justicia carnea (Ewe eje or ogwu obara) are calcium, iron, magnesium, copper and zinc. 2004;19(12):16. Badami S, Aneesh R, Sankar S, Sathishkumar MN, Suresh B, Rajan S. Antifertility activity of Derris brevipes variety coriacea. Article Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. In this study, the aqueous leaf extract of Justicia carnea was used. Treatments of all experimental animals were performed following Principle of Laboratory Animal Care manual guidebook of National Institute of Health as approved by the Research Ethics Committee of Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State. Tissues were processed automatically using automatic tissue processor (Leica TP 1020) and allowed to pass through varying percentage of alcohol and absolute alcohol for the purpose of dehydration following dewaxing in Xylene for 15mins. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Methods. leaf inhibits interferon-γ secretion and has bacteriostatic activity against Acinetobacter baumannii and Klebsiella pneumoniae. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. J Ethnopharmacol. Google Scholar. Tips on how to get rid of leaf eating caterpillar. Ethanol extract of J. carnea leaf elevated red blood cell, hemoglobin, packed cell volume and platelet count with significant increase at higher doses of extracts compared to the control. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. View abstract. https://doi.org/10.3390/molecules191221442. 5. Ewe eje can increase blood count and volume. Biomed Environ Mass Spectrom 1988;15(8):413-417. It is an awesome plant and worth your time and attention. Vitamin B aids in the formation of red blood cells and helps to build tissues. Google Scholar. The plant produces dark green leaves around 8 inches in length. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. The shrubby habit of the plant is well-suited for both containers and outside planting. Further, 0.5ml of supernatant was treated with 0.5ml of Ellmans reagent (containing 19.8mg of 5,5 dithiobis - (2-nitrobenzoic acid) (DTNB) in 100ml of 0.1% sodium nitrate) and 3.0ml of phosphate buffer (0.2M, pH8.0). Ren Fail. Influence of ethanolic extracts of dried fruit of Xylopia aethiopica (Dunal) A. 15 Amazing benefits of brocoli juice and side effects. Check these Great Plant Combination Ideas with Justicia, Eye-Catching Retaining Walls and Staircases, An Eye-Catching Mediterranean Garden with Agave, Aloe and Pincushion, A Striking Water-Wise Border with Agave, Cactus and Ocotillo, A Beautiful Duo with Agave 'Blue Flame' and 'Blue Glow', A Long-Lasting Summer Garden Idea with Marigold and Sage, 8, 9, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, H1, H2. 2010;4(8):6804 https://doi.org/10.5897/JMPR09.487. 2002;82:197205. DOI: https://doi.org/10.1089/ars.2007.1901. The flowers are slightly fragrant and mostly sterile. However, coadministration of both extracts exerts a synergistic effecton the . It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. 50mg/kg-1200mg/kg treatment relative to control treatment showed varied degree of renal injury that is dose dependent. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. Too much sun can scorch the leaves, and too little will result in fewer flowers. In some areas, the plant may tolerate temperatures as low as 50 degrees Fahrenheit (10 C). The unique and beautiful tubular flowers of Justicia carnea highlight the plant. Chidubem Olovo is a biochemist and a researcher whose interest is centered on the chemistry of natural products, their pharmacological properties and how using the plant sources can improve human healthy living. During the growing season, the justicia (plant) should be watered thoroughly with room temperature water. 1972;47:38994. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). Ashwagandha tea: 10 benefits, side effects and recipes, 7 interesting health facts about Black sapote fruits. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. In its native habitat, the Justicia carnea plant grows upright and may reach 3 5 feet tall. Mounanga MB, Mewonob L, Angone SA. Details on Purple Shield plant care. These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. It has already been pointed out that this plant is used traditionally to boost blood production among the people of southern Nigeria. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Beijing: Chemical Press; 2011. Justicia carnea is affects Fertility according to a researched article published on ResearchgateJusticia carnea was found to lower sperm count Male Wistar Albino ratsthe effect of this herb on female fertility is not yet known. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. The renal effects of blood glucose-lowering plant-derived extracts in diabetes mellitus-an overview. Meth Enzymol. When it comes to blood boosting and treatment of anemia, justicia carnea has proven beyond doubt to be an effective remedy. 1978;90:819. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. Control treatment showed normal central venules without congestion, the morphology of the hepatocytes appear normal, the sinusoids appear normal with no observable form of infiltration and no observable pathological lesion seen. Control treated group showed normal micromorphological sections. The catalase activity was calculated using the expression: Note: A=change in absorbance, TV=total volume, TP=total protein, SV=sample volume, =molar extinction=40M1 cm1. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. aqueous extract J. carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male Wistar albino rats. long (20 cm), densely packed with pink to crimson tubular flowers. Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. California Privacy Statement, Mapanga RF, Musabayane CT. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. Stover PJ, Caudill MA. The mixture was allowed to cool and centrifuged at 650g for 10min to obtain the supernatant. Infertility after therapy, in particular, imposes a significant mental strain on young patients. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases.
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